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KMID : 0387420100210040041
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Korean Society of Oriental Neuropsychiatry
2010 Volume.21 No. 4 p.41 ~ p.51
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Immuno stimulatory activities of Samul-tang, Sagunja-tang, Pamul-tang and Sipjeondaebo-tang in vitro
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Lee Ho-Young
Ha Hye-Kyung
Jung Da-Young
Lee Nam-Hun
Shin Hyeun-Kyoo
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Abstract
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Objectives: Samul-tang(SM). Sagunja-tang(SG). Pamul-tang(PM) and Sipjeondaebo-tang(SJ) was used many diseases such as sterility. menstrual disorder. general prostration. recruitment in Korea. We investigated the immune stimulatory activities of SG. SM. PM and SJ in jn vitro.
Methods: For comparision for effective of SM. SG. PM and SJ. this study examined anti-inflammation(NO. PGE2 assay). anti-oxidation(DPPH assay) and immune response in in vitro assay. For immune response activities. this study used NO synthesis on RAW 264.7 cells, splenocyte proliferation and cytokine assay(IL-2, IL-4) in splenocyte.
Results: The results showed that SG. SM. PM and SJ were no significant effect anti-oxidation and anti-inflammatory effects. For immune response. they showed the splenocyte proliferation and macrophage proliferation. We confirmed that they synthesised NO a dose-dependent manner significantly and secreted the IL-4.
Conclusions: These results suggested the SG, SM, PM and SJ had immune stimulatory activity. A efficacy of immune response in them had produced similar results.
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KEYWORD
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Samul-tang, Sagunja-tang, Pamul-tang, Sipjeondaebo-tang, Immune stimulatory activity
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